Speakers articles

Take a look at what some of our invited speakers have published recently and chat with them about their work in Sitges, Spain at our symposium.

Keynote Speakers

David Sabatini, Whitehead Institute, USA
Sestrin2 is a leucine sensor for the mTORC1 pathway
An Essential Role of the Mitochondrial Electron Transport Chain in Cell Proliferation Is to Enable Aspartate Synthesis
Disruption of the Rag-Ragulator Complex by c17orf59 Inhibits mTORC1


Rozalyn Anderson, University of Wisconsin, USA
Regional metabolic heterogeneity of the hippocampus is nonuniformly impacted by age and caloric restriction

Johan Auwerx, EPFL, Switzerland
NAD+ Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus

Anne Brunet, Stanford University, USA
Lipid Profiles and Signals for Long Life
The African Turquoise Killifish Genome Provides Insights into Evolution and Genetic Architecture of Lifespan
A platform for rapid exploration of aging and diseases in a naturally short-lived vertebrate

Andrew Dillin, University of California at Berkeley, USA
Autophagy-mediated longevity is modulated by lipoprotein biogenesis
Heterotypic Signals from Neural HSF-1 Separate Thermotolerance from Longevity
The Deubiquitylase MATH-33 Controls DAF-16 Stability and Function in Metabolism and Longevity

Malene Hansen, Sanford Burnham Prebys Medical Discovery Institute, USA
Transcriptional and epigenetic regulation of autophagy in aging.

Tamas Horvath, Yale University, USA
Mitochondrial ROS Signaling in Organismal Homeostasis

Heinrich Jasper, Buck Institute, USA
Of Flies, Mice, and Men: Evolutionarily Conserved Tissue Damage Responses and Aging
PGRP-SC2 Promotes Gut Immune Homeostasis to Limit Commensal Dysbiosis and Extend Lifespan
Hypothalamic Agrp Neurons Drive Stereotypic Behaviors beyond Feeding

Matt Kaeberlein, University of Washington, USA
Cell nonautonomous activation of flavin-containing monooxygenase promotes longevity and health span

Valter Longo, University of Southern California, USA
The conserved role of protein restriction in aging and disease
A Periodic Diet that Mimics Fasting Promotes Multi-System Regeneration, Enhanced Cognitive Performance, and Healthspan.

Thomas Rando, Stanford University, USA
Stem cells and healthy aging

John Sedivy, Brown University, USA
Reduced Expression of MYC Increases Longevity and Enhances Healthspan

Amita Sehgal, University of Pennsylvania, USA
Peripheral Circadian Clocks Mediate Dietary Restriction-Dependent Changes in Lifespan and Fat Metabolism in Drosophila

Manuel Serrano, CNIO, Madrid
Pharmacological Inhibition of PI3K Reduces Adiposity and Metabolic Syndrome in Obese Mice and Rhesus Monkeys

David Sinclair, Harvard Medical School, USA
When stem cells grow old: phenotypes and mechanisms of stem cell aging.

Timothy Spector, King's College London, UK
The Concordance and Heritability of Type 2 Diabetes in 34,166 Twin Pairs From International Twin Registers: The Discordant Twin (DISCOTWIN) Consortium.

Kicking Back Cognitive Ageing: Leg Power Predicts Cognitive Ageing after Ten Years in Older Female Twins

Yousin Suh, Albert Einstein College of Medicine, NY, USA
Genetic evidence for common pathways in human age-related diseases.

Supporting Publications
Platinum Sponsor
Travel Award